Crystallization (Comment) | Organism |
---|---|
in complex with product, 1-methyl nicotinamide, and demethylated cofactor, S-adenosyl-homocysteine, to 1.88 A resolution. 1-methyl nicotinamide binds to the active site and it would be trapped in the active site due to the formation of the bridge between the pole and long C-terminal loop | Mus musculus |
in complex with product, 1-methyl nicotinamide, and demethylated cofactor, S-adenosyl-homocysteine, to 1.88 A resolution. 1-methyl nicotinamide binds to the active site and it would be trapped in the active site due to the formation of the bridge between the pole and long C-terminal loop | Macaca mulatta |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-methyl nicotinamide | feedback inhibitor | Macaca mulatta | |
1-methyl nicotinamide | feedback inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Macaca mulatta | F7ERX8 | - |
- |
Mus musculus | O55239 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-adenosyl-L-methionine + nicotinamide | - |
Mus musculus | S-adenosyl-L-homocysteine + 1-methylnicotinamide | - |
? | |
S-adenosyl-L-methionine + nicotinamide | - |
Macaca mulatta | S-adenosyl-L-homocysteine + 1-methylnicotinamide | - |
? |