Application | Comment | Organism |
---|---|---|
drug development | the enzyme might be a good molecular target for lung cancer therapy | Homo sapiens |
pharmacology | the enzyme might be a good molecular target for lung cancer therapy | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
quantitative real-time PCR enzyme expression analysis in non-smalll cell lung cancer samples | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | - |
Homo sapiens | - |
lung cancer cell | - |
Homo sapiens | - |
additional information | quantitative real-time PCR enzyme expression analysis | Homo sapiens | - |
non-small cell lung cancer cell | the cells show enzyme overexpression compared to both tumor-adjacent and surrounding tissue | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
NNMT | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | shRNA-mediated gene silencing of NNMT leads to a significntl inhibition of cell proliferation and colony formation ability, downregulation of the enzyme significantly reduces the tumorigenicity of A-549 cells | Homo sapiens |
physiological function | role of nicotinamide N-methyltransferase in non-small cell lung cancer | Homo sapiens |