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Literature summary for 1.8.99.B2 extracted from

  • Liu, Y.; Denkmann, K.; Kosciow, K.; Dahl, C.; Kelly, D.
    Tetrathionate stimulated growth of Campylobacter jejuni identifies a new type of bi-functional tetrathionate reductase (TsdA) that is widely distributed in bacteria (2013), Mol. Microbiol., 88, 173-188.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01
-
tetrathionate pH 5.0, 42°C Campylobacter jejuni

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36247
-
x * 36247, calculated from sequence Campylobacter jejuni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
tetrathionate + a reduced electron acceptor Campylobacter jejuni
-
2 thiosulfate + an oxidized electron acceptor
-
?
tetrathionate + a reduced electron acceptor Campylobacter jejuni NCTC 11828
-
2 thiosulfate + an oxidized electron acceptor
-
?

Organism

Organism UniProt Comment Textmining
Campylobacter jejuni
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Campylobacter jejuni

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
64
-
pH 5.0, 42°C Campylobacter jejuni

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
tetrathionate + a reduced electron acceptor
-
Campylobacter jejuni 2 thiosulfate + an oxidized electron acceptor
-
?
tetrathionate + a reduced electron acceptor bifunctional tetrathionate reductase/thiosulphate dehydrogenase Campylobacter jejuni 2 thiosulfate + an oxidized electron acceptor
-
?
tetrathionate + a reduced electron acceptor
-
Campylobacter jejuni NCTC 11828 2 thiosulfate + an oxidized electron acceptor
-
?
tetrathionate + a reduced electron acceptor bifunctional tetrathionate reductase/thiosulphate dehydrogenase Campylobacter jejuni NCTC 11828 2 thiosulfate + an oxidized electron acceptor
-
?

Subunits

Subunits Comment Organism
? x * 36247, calculated from sequence Campylobacter jejuni

Synonyms

Synonyms Comment Organism
C8J_0815 locus name Campylobacter jejuni
TsdA bifunctional tetrathionate reductase/thiosulfate dehydrogenase Campylobacter jejuni

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
assay at Campylobacter jejuni

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
426
-
tetrathionate pH 5.0, 42°C Campylobacter jejuni

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
assay at Campylobacter jejuni

Cofactor

Cofactor Comment Organism Structure
heme sequence shows two Cys-X2-Cys-His heme c-binding motifs, bifunctional tetrathionate reductase/thiosulphate dehydrogenase Campylobacter jejuni

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
42600
-
tetrathionate pH 5.0, 42°C Campylobacter jejuni