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Literature summary for 1.8.98.1 extracted from

  • Ehrenfeld, N.; Levican, G.; Parada, P.
    Heterodisulfide reductase from Acidithiobacilli is a key component involved in metabolism of reduced inorganic sulfur compounds (2013), Adv. Mater. Res., 825, 194-197 .
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
coenzyme B + coenzyme M + methanophenazine Acidithiobacillus ferrooxidans
-
N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine Acidithiobacillus thiooxidans
-
N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine Acidithiobacillus thiooxidans DSM 17318
-
N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine Acidithiobacillus ferrooxidans DSM 16786
-
N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?

Organism

Organism UniProt Comment Textmining
Acidithiobacillus ferrooxidans
-
-
-
Acidithiobacillus ferrooxidans DSM 16786
-
-
-
Acidithiobacillus thiooxidans
-
-
-
Acidithiobacillus thiooxidans DSM 17318
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
coenzyme B + coenzyme M + methanophenazine
-
Acidithiobacillus ferrooxidans N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine
-
Acidithiobacillus thiooxidans N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine
-
Acidithiobacillus thiooxidans DSM 17318 N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?
coenzyme B + coenzyme M + methanophenazine
-
Acidithiobacillus ferrooxidans DSM 16786 N-[7-[(2-sulfoethyl)dithio]heptanoyl]-O3-phospho-L-threonine + dihydromethanophenazine
-
?

Synonyms

Synonyms Comment Organism
HDR
-
Acidithiobacillus ferrooxidans
HDR
-
Acidithiobacillus thiooxidans
HdrA subunit Acidithiobacillus ferrooxidans
HdrA subunit Acidithiobacillus thiooxidans
HdrB1 subunit Acidithiobacillus ferrooxidans
HdrB1 subunit Acidithiobacillus thiooxidans
HdrB2 subunit Acidithiobacillus ferrooxidans
HdrB2 subunit Acidithiobacillus thiooxidans
HdrC1 subunit Acidithiobacillus ferrooxidans
HdrC1 subunit Acidithiobacillus thiooxidans
HdrC2 subunit Acidithiobacillus ferrooxidans
HdrC2 subunit Acidithiobacillus thiooxidans
heterodisulfide reductase
-
Acidithiobacillus ferrooxidans
heterodisulfide reductase
-
Acidithiobacillus thiooxidans

Expression

Organism Comment Expression
Acidithiobacillus thiooxidans the hdr enzyme genes are highly expressed when bacteria are grown in the presence of sulfur and tetrathionate up
Acidithiobacillus ferrooxidans the hdr enzyme genes are highly expressed when bacteria are grown in the presence of sulfur and tetrathionate. Moreover, hdr genes in are greatly up-regulated when grown in sulfur compared to ferrous medium up