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Literature summary for 1.8.7.2 extracted from

  • Cejudo, F.J.; Gonzalez, M.C.; Perez-Ruiz, J.M.
    Redox regulation of chloroplast metabolism (2021), Plant Physiol., 186, 9-21 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.7.2

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
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 Arabidopsis thaliana 9507
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 reduced ferredoxin + thioredoxin disulfide Arabidopsis thaliana
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 2 oxidized ferredoxin + thioredoxin + 2 H+
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 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q9SJ89
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-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
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 Arabidopsis thaliana
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 reduced ferredoxin + thioredoxin disulfide
-
 Arabidopsis thaliana 2 oxidized ferredoxin + thioredoxin + 2 H+
-
 ?
additional information typical chloroplast thioredoxins (TRXs) include those of types m (four isoforms), f (two isoforms), y (two isoforms), x, and z. The redox regulation of enzymes of the Calvin-Benson cycle (CBC) and show the relevance of f-type TRXs in the light-dependent regulation of carbon fixation Arabidopsis thaliana ?
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Synonyms

Synonyms Comment Organism
FDX-dependent TRX reductase
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 Arabidopsis thaliana
FTR
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 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
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 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction Arabidopsis thaliana mutants with decreased contents of the catalytic subunit of FTR (FTRc), hence with impaired fuel of electrons into the pathway, show severe chlorosis in leaf sectors near the petiole, similar to the phenotype of mutant plants with lower FTR activity. In contrast, the deficiency of individual TRXs has low effect on growth phenotype indicating functional redundancy of the different plastid TRXs, except TRX z since mutants lacking this TRX show an albino phenotype Arabidopsis thaliana
metabolism the FDX-FTR-TRXs pathway allows the regulation of redox-sensitive chloroplast enzymes in response to light. In addition, chloroplasts contain an NADPH-dependent redox system, termed NTRC, which allows the use of NADPH in the redox network of these organelles. NTRC is required for the activity of TRXs. Genetic approaches using mutants of Arabidopsis thaliana in combination with biochemical and physiological studies show that both redox systems, NTRC and FDX-FTR-TRXs, participate in fine-tuning chloroplast performance in response to changes in light intensity. Moreover, these studies reveal the participation of 2-Cys peroxiredoxin (2-Cys PRX), a thiol-dependent peroxidase, in the control of the reducing activity of chloroplast TRXs as well as in the rapid oxidation of stromal enzymes upon darkness. Analysis of functional relationship of 2-Cys PRXs with NTRC and the FDX-FTR-TRXs redox systems for fine-tuning chloroplast performance in response to changes in light intensity and darkness, overview. NTRC and FDX-FTR-TRXs pathway are integrated by the redox balance of 2-Cys PRXs. Redox regulation is an additional layer of control of the signaling function of the chloroplast Arabidopsis thaliana
physiological function regulation of enzyme activity based on thiol-disulfide exchange is a regulatory mechanism in which the protein disulfide reductase activity of thioredoxins (TRXs) plays a central role. Plant chloroplasts are equipped with a complex set of up to 20 TRXs and TRX-like proteins, the activity of which is supported by reducing power provided by photosynthetically reduced ferredoxin (FDX) with the participation of a FDX-dependent TRX reductase (FTR). The complex redox network composed of the FDX-FTR-TRXs pathway links redox regulation to light. Therefore, the FDX-FTR-TRXs pathway allows the regulation of redox-sensitive chloroplast enzymes in response to light. Involvement of redox regulation in chloroplast retrograde signaling modulates early stages of plant development and response to environmental stress, overview. Ferredoxin, FDX, the final acceptor of the photosynthetic electron transport chain, fuels reducing equivalents to plastid thioredoxins (TRXs) with the participation of FTR Arabidopsis thaliana