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Literature summary for 1.8.5.8 extracted from
- Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria (2008), FEBS J., 275, 3352-3361 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| H2S | the enzyme activity decreases when the ambient sulfide concentration exceeds 0.3 mM | Rattus norvegicus |  |
| additional information | not inhibited by up to 2 mM H2S | Arenicola marina |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00287 | - |
hydrogen sulfide | at pH 7.4 and 25°C | Rattus norvegicus | |
| 0.00994 | - |
hydrogen sulfide | at pH 7.4 and 25°C | Arenicola marina | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Rattus norvegicus | 5739 | - |
| mitochondrion | - |
Arenicola marina | 5739 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydrogen sulfide + glutathione + a quinone | Rattus norvegicus | - |
S-sulfanylglutathione + a quinol | - |
? | |
| hydrogen sulfide + glutathione + a quinone | Arenicola marina | - |
S-sulfanylglutathione + a quinol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arenicola marina | B0LD08 | - |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Resource Q column chromatography, Source S column chromatography, and Superdex 75 gel filtration | Rattus norvegicus |
| Resource Q column chromatography, Source S column chromatography, and Superdex 75 gel filtration | Arenicola marina |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| hydrogen sulfide + glutathione + a quinone | - |
Rattus norvegicus | S-sulfanylglutathione + a quinol | - |
? | |
| hydrogen sulfide + glutathione + a quinone | - |
Arenicola marina | S-sulfanylglutathione + a quinol | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SQR | - |
Rattus norvegicus |
| SQR | - |
Arenicola marina |
| sulfide : quinone oxidoreductase | - |
Rattus norvegicus |
| sulfide : quinone oxidoreductase | - |
Arenicola marina |
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Release 2023.1 (January 2023)
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