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Literature summary for 1.8.5.4 extracted from
- Sulfide:quinone oxidoreductase (SOR) from the lugworm Arenicola marina shows cyanide- and thioredoxin-dependent activity (2008), FEBS J., 275, 1131-1139.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| cyanide | SQR isolated from yeast mitochondria reduces decyl-ubiquinone after the addition of sulfide only in the presence of cyanide | Arenicola marina |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Saccharomyces cerevisiae | Arenicola marina |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| antimycin A | competitive inhibition | Arenicola marina | |
| cyanide | substrate inhibition | Arenicola marina | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0064 | - |
decylubiquinone | 20 mM Tris-HCl, pH 8.0, at 22°C | Arenicola marina | |
| 0.23 | - |
Sulfide | 20 mM Tris-HCl, pH 8.0, at 22°C | Arenicola marina | |
| 2.6 | - |
cyanide | 20 mM Tris-HCl, pH 8.0, at 22°C | Arenicola marina | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrial membrane | - |
Arenicola marina | 31966 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arenicola marina | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography | Arenicola marina |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| sulfide + decylubiquinone + cyanide | - |
Arenicola marina | sulfur + decylubiquinol + thiocyanate | - |
? | |
| sulfide + decylubiquinone + Escherichia coli thioredoxin | with Escherichia coli thioredoxin, SQR exhibits one-tenth of the cyanide-dependent activity | Arenicola marina | sulfur + decylubiquinol + ? | - |
? | |
| sulfide + decylubiquinone + sulfite | with sulfite, SQR exhibits one-tenth of the cyanide-dependent activity | Arenicola marina | sulfur + decylubiquinol + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SQR | - |
Arenicola marina |
| sulfide:quinone oxidoreductase | - |
Arenicola marina |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | - |
- |
Arenicola marina |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Arenicola marina | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.7 | - |
cyanide | 20 mM Tris-HCl, pH 8.0, at 22°C | Arenicola marina | |
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