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Literature summary for 1.8.4.16 extracted from

  • Stewart, E.; Katzen, F.; Beckwith, J.
    Six conserved cysteines of the membrane protein DsbD are required for the transfer of electrons from the cytoplasm to the periplasm of Escherichia coli (1999), EMBO J., 18, 5963-5971 .
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
C122A active site mutant Escherichia coli
C128A active site mutant Escherichia coli
C13A the mutant shows wild type activity Escherichia coli
C182A active site mutant Escherichia coli
C301A the mutant shows wild type activity Escherichia coli
C304A active site mutant Escherichia coli
C480A/C483A active site mutant Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane
-
Escherichia coli
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [protein] with reduced L-cysteine residues + thioredoxin disulfide Escherichia coli overall reaction a [protein] carrying a disulfide bond + thioredoxin
-
?
[DsbC protein] carrying a disulfide bond + thioredoxin Escherichia coli
-
[DsbC protein] with reduced L-cysteine residues + thioredoxin disulfide
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [protein] with reduced L-cysteine residues + thioredoxin disulfide overall reaction Escherichia coli a [protein] carrying a disulfide bond + thioredoxin
-
?
[DsbC protein] carrying a disulfide bond + thioredoxin
-
Escherichia coli [DsbC protein] with reduced L-cysteine residues + thioredoxin disulfide
-
?

Synonyms

Synonyms Comment Organism
DsbD
-
Escherichia coli