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Literature summary for 1.8.4.15 extracted from

  • Davey, L.; Ng, C.; Halperin, S.; Lee, S.
    Functional analysis of paralogous thiol-disulfide oxidoreductases in Streptococcus gordonii (2013), J. Biol. Chem., 288, 16416-16429 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) cells Streptococcus gordonii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS Streptococcus gordonii autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity ?
-
?
a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS Streptococcus gordonii SecCR1 autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity ?
-
?

Organism

Organism UniProt Comment Textmining
Streptococcus gordonii
-
-
-
Streptococcus gordonii SecCR1
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity Streptococcus gordonii ?
-
?
a [DsbA protein] carrying a disulfide bond + N-acetylmuramidase/lysin AtlS autolysin AtlS requires the enzyme for the formation of an intramolecular disulfide bond between residues Cys1048 and Cys1069. This bond is essential for processing and enzymatic activity Streptococcus gordonii SecCR1 ?
-
?

Synonyms

Synonyms Comment Organism
SdbA
-
Streptococcus gordonii
Streptococcus disulfide bond protein A
-
Streptococcus gordonii
TDOR
-
Streptococcus gordonii
thiol-disulfide oxidoreductase
-
Streptococcus gordonii

General Information

General Information Comment Organism
metabolism the enzyme is required for production of disulfide-bonded proteins Streptococcus gordonii