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Literature summary for 1.8.4.12 extracted from
- Structural insights into interaction between mammalian methionine sulfoxide reductase B1 and thioredoxin (2012), J. Biomed. Biotechnol., 2012, 586539.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli ER2566 cells | Mus musculus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-methionine (R)-sulfoxide + thioredoxin | Mus musculus | MsrB is stereospecific for the R-epimer of methionine sulfoxide | L-methionine + thioredoxin disulfide + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | Q9JLC3 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Ni-NTA column chromatography, and gel filtration | Mus musculus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| dabsyl-L-methionine (R)-sulfoxide + thioredoxin | - |
Mus musculus | dabsyl-L-methionine + thioredoxin disulfide + H2O | - |
? | |
| L-methionine (R)-sulfoxide + thioredoxin | MsrB is stereospecific for the R-epimer of methionine sulfoxide | Mus musculus | L-methionine + thioredoxin disulfide + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| methionine sulfoxide reductase B1 | - |
Mus musculus |
| MSRB1 | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| thioredoxin | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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