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Literature summary for 1.8.4.12 extracted from

  • Pascual, I.; Larrayoz, I.M.; Campos, M.M.; Rodriguez, I.R.
    Methionine sulfoxide reductase B2 is highly expressed in the retina and protects retinal pigmented epithelium cells from oxidative damage (2010), Exp. Eye Res., 90, 420-428.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.4.12

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-
mitochondrion
-
 Macaca mulatta 5739
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Macaca mulatta
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain cortex
-
 Homo sapiens
-
cerebellum
-
 Homo sapiens
-
D-407 cell
-
 Homo sapiens
-
heart highest expression Homo sapiens
-
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
lung
-
 Homo sapiens
-
placenta
-
 Homo sapiens
-
prostate
-
 Homo sapiens
-
retina
-
 Homo sapiens
-
retina ethionine sulfoxide reductase B2 is highly expressed in the retina, in the monkey retina MSRB2 localizes to the ganglion cell layer, the outer plexiform layer and the retinal pigment epithelium Macaca mulatta
-
retinal pigment epithelium
-
 Macaca mulatta
-
skeletal muscle
-
 Homo sapiens
-
small intestine
-
 Homo sapiens
-
spleen
-
 Homo sapiens
-
stomach
-
 Homo sapiens
-
testis
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dabsyl-L-methionine (R)-sulfoxide + dithiothreitol
-
 Homo sapiens dabsyl-L-methionine + dithiothreitol disulfide + H2O
-
 ?
dabsyl-L-methionine (R)-sulfoxide + dithiothreitol
-
 Macaca mulatta dabsyl-L-methionine + dithiothreitol disulfide + H2O
-
 ?

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase B2
-
 Homo sapiens
methionine sulfoxide reductase B2
-
 Macaca mulatta
MsrB2
-
 Homo sapiens
MsrB2
-
 Macaca mulatta

General Information

General Information Comment Organism
physiological function MSRB2 plays an important function in protecting cones from multiple type of oxidative stress and is critical in preserving central vision Homo sapiens
physiological function MSRB2 plays an important function in protecting cones from multiple type of oxidative stress and is critical in preserving central vision Macaca mulatta