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Literature summary for 1.8.4.11 extracted from

  • Das, K.; Garnica, O.; Flores, J.; Dhandayuthapani, S.
    Methionine sulfoxide reductase A (MsrA) modulates cells and protects against Mycoplasma genitalium induced cytotoxicity (2020), Free Radic. Biol. Med., 152, 323-335 .
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Mycoplasma pneumoniae
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-
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Purification (Commentary)

Purification (Comment) Organism
-
Mycoplasma pneumoniae

Synonyms

Synonyms Comment Organism
methionine sulfoxide reductase A
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Mycoplasma pneumoniae
MsrA
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Mycoplasma pneumoniae

General Information

General Information Comment Organism
malfunction lack of or overexpression of MsrA in cells affects the function of proteins and can lead to altered cellular processes Mycoplasma pneumoniae
metabolism HeLa cells pretreated with MsrA secrete reduced levels of TNF-alpha following Mycoplasma genitalium infection. MsrA treatment of cells affects the phosphorylation status of transcriptional regulators such as NF-kappaB, JNK and p53 that regulate different cytokines Mycoplasma pneumoniae
physiological function antioxidant repair enzyme. Secreted MsrA may help pathogens to modulate host cellular processes Mycoplasma pneumoniae