Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycoplasma pneumoniae | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mycoplasma pneumoniae |
Synonyms | Comment | Organism |
---|---|---|
methionine sulfoxide reductase A | - |
Mycoplasma pneumoniae |
MsrA | - |
Mycoplasma pneumoniae |
General Information | Comment | Organism |
---|---|---|
malfunction | lack of or overexpression of MsrA in cells affects the function of proteins and can lead to altered cellular processes | Mycoplasma pneumoniae |
metabolism | HeLa cells pretreated with MsrA secrete reduced levels of TNF-alpha following Mycoplasma genitalium infection. MsrA treatment of cells affects the phosphorylation status of transcriptional regulators such as NF-kappaB, JNK and p53 that regulate different cytokines | Mycoplasma pneumoniae |
physiological function | antioxidant repair enzyme. Secreted MsrA may help pathogens to modulate host cellular processes | Mycoplasma pneumoniae |