BRENDA - Enzyme Database show
show all sequences of 1.8.3.5

Proteome of human plasma very low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid metabolism

Dashty, M.; Motazacker, M.M.; Levels, J.; de Vries, M.; Mahmoudi, M.; Peppelenbosch, M.P.; Rezaee, F.; Thromb. Haemost. 111, 518-530 (2014)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
extracellular
-
Homo sapiens
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
Q9UHG3
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
plasma
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
an S-prenyl-L-cysteine + O2 + H2O
-
743865
Homo sapiens
a prenal + L-cysteine + H2O2
-
-
-
?
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
extracellular
-
Homo sapiens
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
plasma
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
an S-prenyl-L-cysteine + O2 + H2O
-
743865
Homo sapiens
a prenal + L-cysteine + H2O2
-
-
-
?
General Information
General Information
Commentary
Organism
metabolism
apart from transporting lipids through the body, the human plasma lipoproteins very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are also thought to serve as a modality for intra-organismal protein transfer, shipping proteins with important roles in inflammation and thrombosis from the site of synthesis to effector locations. Prenylcysteine oxidase 1, like dermcidin, cathelicidin antimicrobial peptide, TFPI-1 and fibrinogen alpha chain, is associated with both VLDL and LDL in human plasma. Analysis of VLDL- and LDL-associated proteins, overview
Homo sapiens
General Information (protein specific)
General Information
Commentary
Organism
metabolism
apart from transporting lipids through the body, the human plasma lipoproteins very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are also thought to serve as a modality for intra-organismal protein transfer, shipping proteins with important roles in inflammation and thrombosis from the site of synthesis to effector locations. Prenylcysteine oxidase 1, like dermcidin, cathelicidin antimicrobial peptide, TFPI-1 and fibrinogen alpha chain, is associated with both VLDL and LDL in human plasma. Analysis of VLDL- and LDL-associated proteins, overview
Homo sapiens
Other publictions for EC 1.8.3.5
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743865
Dashty
Proteome of human plasma very ...
Homo sapiens
Thromb. Haemost.
111
518-530
2014
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710018
Huizinga
Farnesylcysteine lyase is invo ...
Arabidopsis thaliana
Mol. Plant
3
143-155
2010
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1
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1
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6
1
2
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3
1
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2
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706670
Banfi
Proteomic analysis of human lo ...
Homo sapiens
Proteomics
9
1344-1352
2009
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1
1
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710279
Crowell
Arabidopsis thaliana plants po ...
Arabidopsis thaliana, Arabidopsis thaliana Col-0
Plant J.
50
839-847
2007
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1
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1
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1
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2
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5
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4
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1
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1
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3
3
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667445
Wouters
Downregulation of two novel ge ...
Mus musculus
Biochem. Biophys. Res. Commun.
346
491-500
2006
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669763
Lu
Thematic review series: lipid ...
Bos taurus
J. Lipid Res.
47
1352-1357
2006
1
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437708
Beigneux
Prenylcysteine lyase deficienc ...
Mus musculus
J. Biol. Chem.
277
38358-38363
2002
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1
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4
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6
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437709
Digits
Stereospecificity and kinetic ...
Homo sapiens
J. Biol. Chem.
277
41086-41093
2002
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2
2
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