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Literature summary for 1.8.3.5 extracted from

  • Lu, J.Y.; Hofmann, S.L.
    Thematic review series: lipid posttranslational modifications. Lysosomal metabolism of lipid-modified proteins (2006), J. Lipid Res., 47, 1352-1357.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
FAD
-
Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00069
-
farnesylcysteine
-
Bos taurus
0.00084
-
geranylgeranylcysteine
-
Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Bos taurus 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
63000
-
SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
column chromatography Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl-L-cysteine + O2 + H2O
-
Bos taurus farnesal + L-cysteine + H2O2
-
?
geranylgeranyl-L-cysteine + O2 + H2O
-
Bos taurus geranylgeranal + L-cysteine + H2O2
-
?
S-prenyl-L-cysteine + O2 + H2O
-
Bos taurus prenal + L-cysteine + H2O2
-
?

Synonyms

Synonyms Comment Organism
flavin adenine dinucleotide (FAD)-dependent thioether oxidase
-
Bos taurus
PCL
-
Bos taurus
prenylcysteine lyase
-
Bos taurus