Literature summary for 1.8.3.2 extracted from

Harvey, A.R.; Ward, M.; Archer, D.B.
Identification and characterisation of eroA and ervA, encoding two putative thiol oxidases from Aspergillus niger (2010), Gene, 461, 32-41.

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
endoplasmic reticulum	isoform EroA is retained in the ER lumen by a C-terminal retention motif	Aspergillus niger	5783	-

Organism

Organism	UniProt	Comment	Textmining
Aspergillus niger	-	-	-
Aspergillus niger N402	-	-	-

Expression

Organism	Comment	Expression
Aspergillus niger	isoform ErvA is slightly downregulated in response to dithiothreitol stress yet up-regulated in response to expression of a heterologous protein	additional information
Aspergillus niger	isoform EroA is transcriptionally up-regulated in response to endoplasmic reticulum stress	up

General Information

General Information	Comment	Organism
physiological function	enzyme gene eroA gene is essential for viability. It is able to complement the ERO1 function in the Saccharomyces cerevisiae ero1-1 mutant	Aspergillus niger
physiological function	isoform ErvA gene ervA does not have an obvious role in the secretion of native proteins, including glucoamylase. It is able to complement the ERO1 function in the Saccharomyces cerevisiae ero1-1 mutant	Aspergillus niger

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Release 2023.1 (January 2023)