Literature summary for 1.8.2.6 extracted from

Zander, U.; Faust, A.; Klink, B.U.; de Sanctis, D.; Panjikar, S.; Quentmeier, A.; Bardischewsky, F.; Friedrich, C.G.; Scheidig, A.J.
Structural basis for the oxidation of protein-bound sulfur by the sulfur cycle molybdohemo-enzyme sulfane dehydrogenase SoxCD (2011), J. Biol. Chem., 286, 8349-8360 .

Cloned(Commentary)

Cloned (Comment)	Organism
-	Paracoccus pantotrophus

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structure of SoxCD1, solved at 1.33 A . SoxCD1 misses the heme-2 domain D2 and is catalytically as active as SoxCD.The substrate of SoxCD is the outer (sulfane) sulfur of Cys-110-persulfide located at the C-terminal peptide swinging arm of SoxY of the SoxYZ carrier complex. The oxidation reactions of the sulfane-sulfur are initiated by the nucleophilic attack of the persulfide anion on the molybdenum atom that is, in turn, reduced. The close proximity of heme-1 to the molybdopterin allows easy acceptance of the electrons	Paracoccus pantotrophus

Crystallization (Comment)

Organism

crystal structure of SoxCD1, solved at 1.33 A . SoxCD1 misses the heme-2 domain D2 and is catalytically as active as SoxCD.The substrate of SoxCD is the outer (sulfane) sulfur of Cys-110-persulfide located at the C-terminal peptide swinging arm of SoxY of the SoxYZ carrier complex. The oxidation reactions of the sulfane-sulfur are initiated by the nucleophilic attack of the persulfide anion on the molybdenum atom that is, in turn, reduced. The close proximity of heme-1 to the molybdopterin allows easy acceptance of the electrons

Paracoccus pantotrophus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Molybdenum	sulfite oxidase-type molybdenum cofactor in subunit SoxC, residue Arg114 involved in the first oxidation step is in close proximity to the molybdenum atiom	Paracoccus pantotrophus

Organism

Organism	UniProt	Comment	Textmining
Paracoccus pantotrophus	-	-	-

Subunits

Subunits	Comment	Organism
heterotetramer	structure resembles a tight alpha2beta-complex with internal 2-fold symmetry, crystallization data	Paracoccus pantotrophus

Synonyms

Synonyms	Comment	Organism
sulfite-dehydrogenase	-	Paracoccus pantotrophus

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Release 2023.1 (January 2023)