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Literature summary for 1.8.2.3 extracted from

  • Lue, C.; Xia, Y.; Liu, D.; Zhao, R.; Gao, R.; Liu, H.; Xun, L.
    Cupriavidus necator H16 uses flavocytochrome c sulfide dehydrogenase to oxidize self-produced and added sulfide (2017), Appl. Environ. Microbiol., 83, e01610-17 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.8.2.3

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hydrogen sulfide + 2 ferricytochrome c Cupriavidus necator without sulfide:quinone oxidoreductase (SQR) Cupriavidus necator H16 uses flavocytochrome c sulfide dehydrogenase (FCSD) to oxidize self-produced sulfide sulfur + 2 ferrocytochrome c + 2 H+
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Organism

Organism UniProt Comment Textmining
Cupriavidus necator WP_010812125.1 AND WP_011616200.1 WP_010812125.1: FccA, WP_011616200.1: FccB
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
hydrogen sulfide + 2 ferricytochrome c
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 Cupriavidus necator sulfur + 2 ferrocytochrome c + 2 H+
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 ?
hydrogen sulfide + 2 ferricytochrome c without sulfide:quinone oxidoreductase (SQR) Cupriavidus necator H16 uses flavocytochrome c sulfide dehydrogenase (FCSD) to oxidize self-produced sulfide Cupriavidus necator sulfur + 2 ferrocytochrome c + 2 H+
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 ?

Synonyms

Synonyms Comment Organism
FCSD
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 Cupriavidus necator
flavocytochrome c sulfide dehydrogenase
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 Cupriavidus necator

General Information

General Information Comment Organism
metabolism without sulfide:quinone oxidoreductase (SQR) Cupriavidus necator H16 uses flavocytochrome c sulfide dehydrogenase (FCSD) to oxidize self-produced sulfide and FCSD couples with persulfide dioxygenase (PDO) to oxidize sulfide to sulfite and thiosulfate, via a pathway similar to the SQR-PDO pathway Cupriavidus necator
physiological function the enzyme plays a detoxification role in Cupriavidus necator H16. With the fccA and fccB genes encoding flavocytochrome c sulfide dehydrogenases Cupriavidus necator H16 oxidizes self-produced H2S Cupriavidus necator