Literature summary for 1.8.1.B1 extracted from

Changklungmoa, N.; Kueakhai, P.; Sangpairoj, K.; Chaichanasak, P.; Jaikua, W.; Riengrojpitak, S.; Sobhon, P.; Chaithirayanon, K.
Molecular cloning and characterization of Fasciola gigantica thioredoxin-glutathione reductase (2015), Parasitol. Res., 114, 2119-2127 .

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Fasciola gigantica

Organism

Organism	UniProt	Comment	Textmining
Fasciola gigantica	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
egg	-	Fasciola gigantica	-
integument	tegument and tegumental cell of juveniles and adults	Fasciola gigantica	-
juvenile	tegument and tegumental cell of 2- and 4-week-old juveniles	Fasciola gigantica	-
additional information	no expression in caecum, muscle, and parenchyma of juvenile nor in spine and muscle of adult	Fasciola gigantica	-
ovary	-	Fasciola gigantica	-
parenchyma	of adult	Fasciola gigantica	-
testis	-	Fasciola gigantica	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH + H+	-	Fasciola gigantica	2-nitro-5-thiobenzoate + NADP+	-	?
beta-hydroxyethyl disulfide + NADPH + H+	-	Fasciola gigantica	2 2-sulfanylethan-1-ol + NADP+	-	?

Subunits

Subunits	Comment	Organism
?	x * 65800, cytosolic isoform, x * 65800, mature mitochondrial isoform, x * 66000, SDS-PAGE of recombinant protein	Fasciola gigantica

Cofactor

Cofactor	Comment	Organism	Structure
NADPH	-	Fasciola gigantica

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Release 2023.1 (January 2023)