Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Schistosoma mansoni |
Crystallization (Comment) | Organism |
---|---|
TGR alone or in complex with NADH and GSSG, sitting drop vapor diffusion method, using 0.1 M HEPES, pH 7.4, 20% PEG 3350, 0.2 M KI and 5 mM beta-mercaptoethanol or 0.2 M magnesium formate, 20% PEG 6000, 0.1 M Hepes, pH 7.0-7.5 and 5 mM beta-mercaptoethanol (TGR with reduced and ordered C-terminus) | Schistosoma mansoni |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
90000 | - |
SDS-PAGE | Schistosoma mansoni |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schistosoma mansoni | Q962Y6 | - |
- |
Purification (Comment) | Organism |
---|---|
- |
Schistosoma mansoni |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
thioredoxin + NADP+ | - |
Schistosoma mansoni | thioredoxin disulfide + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TGR | - |
Schistosoma mansoni |
thioredoxin glutathione reductase | this natural chimeric enzyme is a peculiar fusion of a glutaredoxin domain with a thioredoxin selenocysteine-containing reductase domain | Schistosoma mansoni |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Schistosoma mansoni | |
NADP+ | - |
Schistosoma mansoni |