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Literature summary for 1.8.1.9 extracted from

  • Conterato, G.M.; Augusti, P.R.; Somacal, S.; Einsfeld, L.; Sobieski, R.; Torres, J.R.; Emanuelli, T.
    Effect of lead acetate on cytosolic thioredoxin reductase activity and oxidative stress parameters in rat kidneys (2007), Basic Clin. Pharmacol. Toxicol., 101, 96-100.
    View publication on PubMed

Application

Application Comment Organism
analysis thioredoxin reductase-1 may be an early indicator of acute exposure to low lead doses Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus O89049
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-

Source Tissue

Source Tissue Comment Organism Textmining
kidney lead exposure causes a marked increase in the thioredoxin reductase-1 activity in the kidney of rats. This is the only parameter affected by low lead doses both after acute and chronic exposure Rattus norvegicus
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Synonyms

Synonyms Comment Organism
thioredoxin reductase-1
-
Rattus norvegicus