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Literature summary for 1.8.1.9 extracted from

  • Nalvarte, I.; Damdimopoulos, A.E.; Spyrou, G.
    Human mitochondrial thioredoxin reductase reduces cytochrome c and confers resistance to complex III inhibition (2004), Free Radic. Biol. Med., 36, 1270-1278.
    View publication on PubMed
Search for more literature for 1.8.1.9

Cloned(Commentary)

Cloned (Comment) Organism
HEK-293 cells overexpressing TrxR2 are more resistant to impairment of complex III bypassing function of TrxR2 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
mitochondrion
-
 Homo sapiens 5739
-

Metals/Ions

Metals/Ions Comment Organism Structure
selenium selenoprotein Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens HEK-293 cells overexpressing TrxR2 are more resistant to impairment of complex III bypassing function of TrxR2 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q16881
-
-
Homo sapiens Q9NNW7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 ferricytochrome c + NADH
-
 Homo sapiens 2 ferrocytochrome c + NAD+ + H+
-
 ?
cytochrome c + NADPH
-
 Homo sapiens reduced cytochrome c + NADP+
-
 ?
additional information HEK-293 cells overexpressing TrxR2 are more resistant to impairment of complex III bypassing function of TrxR2 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
TrxR1
-
 Homo sapiens
TrxR2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Homo sapiens
NADPH
-
 Homo sapiens