Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.8.1.9 extracted from

  • Schallreuter, K.U.; Wood, J.M.
    The activity and purification of membrane-associated thioredoxin reductase from human metastatic melanotic melanoma (1988), Biochim. Biophys. Acta, 967, 103-109.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Ca2+
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasmic membrane associated Homo sapiens
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
x * 58000, melanoma metastases, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell metastatic melanotic Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH i.e. DTNB Homo sapiens 2-nitro-5-thiobenzoate + NADP+
-
?
dithiothreitol + NADPH
-
Homo sapiens ?
-
?
thioredoxin + NADP+ coupled assay with DTNB Homo sapiens thioredoxin disulfide + NADPH
-
?
thioredoxin + NADP+ in presence of NADPH, coupled assay Homo sapiens thioredoxin disulfide + NADPH + H+
-
?
thioredoxin + NADP+ i.e. DTNB Homo sapiens thioredoxin disulfide + NADPH + H+
-
?

Subunits

Subunits Comment Organism
? x * 58000, melanoma metastases, SDS-PAGE Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FAD
-
Homo sapiens
NADPH
-
Homo sapiens