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Literature summary for 1.8.1.7 extracted from

  • Sharma, M.; Khanna, S.; Bulusu, G.; Mitra, A.
    Comparative modeling of thioredoxin glutathione reductase from Schistosoma mansoni: a multifunctional target for antischistosomal therapy (2009), J. Mol. Graph. Model., 27, 665-675.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Schistosoma mansoni 5829
-

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni Q962Y6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GSSG + NADPH + H+
-
Schistosoma mansoni GSH + NADP+
-
?

Subunits

Subunits Comment Organism
dimer x-ray crystallography Schistosoma mansoni

Synonyms

Synonyms Comment Organism
TGR
-
Schistosoma mansoni
thioredoxin glutathione reductase multifunctional enzyme involving a fusion of two proteins, glutaredoxin and thioredoxin reductase Schistosoma mansoni

Cofactor

Cofactor Comment Organism Structure
FAD
-
Schistosoma mansoni
NADPH
-
Schistosoma mansoni