Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,3-bis-(2-chloroethyl) 1-nitrosourea | irreversible inhibition | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH | Rattus norvegicus | antioxidant enzyme, protects the pancreatic cell against reactive oxygen species involved in the diabetogenic agent-induced dysfunction of pancreatic-beta-cells | glutathione + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
7-week-old Wistar rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
pancreas | localization of the enzyme in pancreatic tissue, overview | Rattus norvegicus | - |
pancreatic acinar cell | pancreas, lower expression level than in islet cells | Rattus norvegicus | - |
pancreatic islet | high expression level | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione disulfide + NADPH | - |
Rattus norvegicus | glutathione + NADP+ | - |
? | |
glutathione disulfide + NADPH | antioxidant enzyme, protects the pancreatic cell against reactive oxygen species involved in the diabetogenic agent-induced dysfunction of pancreatic-beta-cells | Rattus norvegicus | glutathione + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glutathione reductase | - |
Rattus norvegicus |
GR | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |