Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ketoconazole | 18% enhancement of activity | Naegleria fowleri | |
metronidazole | 68% enhancement of activity | Naegleria fowleri | |
Pentamidine | 40% enhancement of activity | Naegleria fowleri | |
rifampicin | 55% enhancement of activity | Naegleria fowleri |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Amphotericin B | 0.0346 mM, 100% inhibition | Naegleria fowleri | |
chlorpromazine | 0.0896 mM, 80% inhibition | Naegleria fowleri | |
Mepacrine | 0.0672 mM, 70% inhibition | Naegleria fowleri | |
miconazole | 0.064 mM, 100% inhibition | Naegleria fowleri | |
Trifluoperazine | 0.0655 mM, 92% inhibition | Naegleria fowleri |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Naegleria fowleri | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
trypanothione disulfide + NADPH | - |
Naegleria fowleri | trypanothione + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TR | - |
Naegleria fowleri |
trypanothione reductase | - |
Naegleria fowleri |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Naegleria fowleri |