Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.7.3.3 extracted from

  • Estarellas, C.; Frontera, A.; Quinonero, D.; Deya, P.
    Relevant anion-π interactions in biological systems: The case of urate oxidase (2011), Angew. Chem. Int. Ed. Engl., 50, 415-418.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
8-Azaxanthine anion-pi interactions are present in the active site of the enzyme and are energetically favorable. Uric acid and 8-azaxanthine are able to interact favorably with cyanide and chloride ions, respectively and both uric acid and 8-azaxanthine react with water Aspergillus flavus
CN- the presence of residue Phe159 enhances the interaction energy of the anion with the urate pi system Aspergillus flavus

Organism

Organism UniProt Comment Textmining
Aspergillus flavus Q00511
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information anion-pi interactions are present in the active site of the enzyme and are energetically favorable Aspergillus flavus ?
-
?

Synonyms

Synonyms Comment Organism
Uaz
-
Aspergillus flavus