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Literature summary for 1.7.3.3 extracted from

  • Townsend, D.; Lata, G.F.
    Purification of urate oxidase; a sex dependent enzyme from rat liver (1969), Arch. Biochem. Biophys., 135, 166-172.
    View publication on PubMed
Search for more literature for 1.7.3.3

General Stability

General Stability Organism
Repeated freezing and thawing has no effect Rattus norvegicus
urate oxidase from female rat livers is more stable than enzyme from male rat livers Rattus norvegicus
urea, 4 M, several h without loss of activity Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
CN-
-
 Rattus norvegicus
Cu2+
-
 Rattus norvegicus
glycerol
-
 Rattus norvegicus
sucrose
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
urate + O2 + H2O Rattus norvegicus
-
 5-hydroxyisourate + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
9.35
-
 male rats Rattus norvegicus
15.3
-
 female Rattus norvegicus

Storage Stability

Storage Stability Organism
3°C, 0.15% sodium carbonate, several weeks, stable Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
urate + O2 + H2O
-
 Rattus norvegicus 5-hydroxyisourate + H2O2
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5 9.3
-
 Rattus norvegicus