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Literature summary for 1.7.1.7 extracted from
- Guanosine monophosphate reductase from Artemia salina: Inhibition by xanthosine monophosphate and activation by diguanosine tetraphosphate (1976), Biochemistry, 15, 4962-4966.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| diguanosine 5',5'''-(P1-P4-tetraphosphate) | - |
Artemia salina |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| XMP | 0.001 mM, more than 50% inhibition; GTP and diguanosine tetraphosphate counteract inhibition | Artemia salina | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.005 | - |
GMP | two Km values | Artemia salina | |
| 0.05 | - |
GMP | two Km values | Artemia salina | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Artemia salina | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Artemia salina |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cyst | - |
Artemia salina | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.564 | - |
- |
Artemia salina |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, 50% glycerol | Artemia salina |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NADPH + guanosine 5'-phosphate | - |
Artemia salina | NADP+ + inosine 5'-phosphate + NH3 | - |
? | |
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