Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Colchicine | noncompetitive with respect to 9,10-phenanthrenequinone and 1,2-naphthoquinone, uncompetitive with respect to NADPH. Binding of colchicine occurs at or close to the NADPH binding site | Camelus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Camelus sp. | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Camelus sp. | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 1,2-naphthoquinone + NADPH + H+ | - |
Camelus sp. | 2 1,2-naphthosemiquinone + NADP+ | - |
? | |
2 9,10-phenanthrenequinone + NADPH + H+ | - |
Camelus sp. | 2 9,10-phenanthrenesemiquinone + NADP+ | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0015 | - |
pH not specified in the publication, temperature not specified in the publication | Camelus sp. | Colchicine |