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Literature summary for 1.6.5.2 extracted from

  • Bang, H.; Park, S.; Saeidi, S.; Na, H.; Surh, Y.
    Docosahexaenoic acid induces expression of heme oxygenase-1 and NAD(P)H Quinone oxidoreductase through activation of Nrf2 in human mammary epithelial cells (2017), Molecules, 22, E969 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens P15559
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Source Tissue

Source Tissue Comment Organism Textmining
MCF-10A cell
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Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens docosahexaenoic acid, DHA, activates transcription factor Nrf2, possibly through modification of a critical Keap1 cysteine288 residue and protein kinase delta-mediated phosphorylation of Nrf2, leading to upregulation of heme oxygenase HO-1 and NQO1 expression up