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Literature summary for 1.6.3.1 extracted from

  • Riazi, S.; Madala-Halagappa, V.K.; Dantas, A.P.; Hu, X.; Ecelbarger, C.A.
    Sex differences in renal nitric oxide synthase, NAD(P)H oxidase, and blood pressure in obese Zucker rats (2007), Gend. Med., 4, 214-229.
    View publication on PubMed

Application

Application Comment Organism
medicine on a high-salt diet of 4% NaC1, male and obese rats have significantly higher mean arterial blood pressure relative to female and lean rats and reduced renal cortical nitric oxide synthase activity. Lean female rats have the highest outer medullary protein levels of several NADPH oxidase subunits, including gp91phox, p47phox, and p67phox, however, renal NADPH activity is not increased in lean females, but is significantly increased in obese rats of both sexes Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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obese Zucker rats
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Source Tissue

Source Tissue Comment Organism Textmining