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Literature summary for 1.6.3.1 extracted from

  • Chitano, P.; Wang, L.; Mason, S.N.; Auten, R.L.; Potts, E.N.; Foster, W.M.; Sturrock, A.; Kennedy, T.P.; Hoidal, J.R.; Murphy, T.M.
    Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase (2008), Am. J. Physiol. Lung Cell. Mol. Physiol., 294, L139-L148.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine mice deficient in NAD(P)H oxidase p47phox show an increase of 17% of the area occupied by airway smooth muscle cells in trachea, compared with wild-type. They exhibit a significantly reduced airway smooth muscle cell relaxation during electric field stimulation and after the end of stimulation. NAD(P)H oxidase may have a role in the structural arrangement and mechanical properties of the airway tissue Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information mice deficient in NAD(P)H oxidase p47phox show an increase of 17% of the area occupied by airway smooth muscle cells in trachea, compared with wild-type. They exhibit a significantly reduced airway smooth muscle cell relaxation during electric field stimulation and after the end of stimulation Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
trachea NAD(P)H oxidase may have a role in the structural arrangement and mechanical properties of the airway tissue Mus musculus
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