Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-chymotrypsin | desensitization of activity to Ca2+ | Sus scrofa | |
Phenylarsine oxide | partial inactivation and desensitization of activity to Ca2+, effect is completely reversed by addition of 2,3-dimercaptopropanol | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
apical plasma membrane | - |
Sus scrofa | 16324 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | regulates enzyme activity | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD(P)H + H+ + O2 | Sus scrofa | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | NAD(P)+ + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thyroid gland | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NAD(P)H + H+ + O2 | - |
Sus scrofa | NAD(P)+ + H2O2 | - |
? | |
NAD(P)H + H+ + O2 | production of hydrogen peroxide in thyroid gland that is required for thyroid hormone synthesis | Sus scrofa | NAD(P)+ + H2O2 | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.003 | - |
Phenylarsine oxide | 3 nmol/mg protein | Sus scrofa |