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Literature summary for 1.6.2.4 extracted from

  • Zhao, C.; Tang, T.; Feng, X.; Qiu, L.
    Cloning and characterisation of NADPH-dependent cytochrome P450 reductase gene in the cotton bollworm, Helicoverpa armigera (2014), Pest Manag. Sci., 70, 130-139 .
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Helicoverpa armigera 16020
-

Organism

Organism UniProt Comment Textmining
Helicoverpa armigera E0A3A7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adult
-
Helicoverpa armigera
-
cuticle
-
Helicoverpa armigera
-
fat body
-
Helicoverpa armigera
-
larva
-
Helicoverpa armigera
-
midgut
-
Helicoverpa armigera
-
pupa
-
Helicoverpa armigera
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + H+ + ferricytochrome c
-
Helicoverpa armigera NADP+ + ferrocytochrome c
-
?

Subunits

Subunits Comment Organism
? x * 77451, calculated from amino acid sequence Helicoverpa armigera

Synonyms

Synonyms Comment Organism
CPR
-
Helicoverpa armigera
NADPH-dependent cytochrome P450 reductase
-
Helicoverpa armigera

Cofactor

Cofactor Comment Organism Structure
FAD
-
Helicoverpa armigera
FMN
-
Helicoverpa armigera

pI Value

Organism Comment pI Value Maximum pI Value
Helicoverpa armigera calculated from amino acid sequence
-
5.5

Expression

Organism Comment Expression
Helicoverpa armigera the expression level of mRNA is 1.84fold higher in midgut of 5th instars of the Handan susceptible strain than that in pupae, and the level in themidgut of handan fenvalerate resistant strain is 2.02fold higher than that of the Handan susceptible strain. The levels of mRNA are induced by phenobarbital at concentrations of 2 and 4 mg/g, which enhances 5.20 and 17.45fold, respectively, compared to that of the control after 48 h of phenobarbital treatment up

General Information

General Information Comment Organism
physiological function the enzyme is important for the development of Helicoverpa armigera and may play an essential role in the P450-mediated insecticide resistance of Helicoverpa armigera to fenvalerate Helicoverpa armigera