Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | addition of trypsin significantly increases activity in detergent free buffer, no effect in the presence of detergent | Rhizopus stolonifer |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Rhizopus stolonifer |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Rhizopus stolonifer | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
78000 | - |
SDS-PAGE, band is accompanied by two smaller, proteolytic forms of the enzyme formed during solubilization or purification | Rhizopus stolonifer |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome P450 + NADPH | Rhizopus stolonifer | involved in the hydroxylation of progesterone at the 11alpha position | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rhizopus stolonifer | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rhizopus stolonifer |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
NADPH + oxidized hemoprotein = NADP+ + reduced hemoprotein + H+ | at high ionic strength nonclassical two-site ping pong mechanism, at low ionic strength a sequential bisubstrate mechanism | Rhizopus stolonifer |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
mycelium | - |
Rhizopus stolonifer | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome c + NADPH | at high ionic strength nonclassical two-site ping pong mechanism, at low ionic strength a sequential bisubstrate mechanism | Rhizopus stolonifer | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
2 ferricytochrome P450 + NADPH | involved in the hydroxylation of progesterone at the 11alpha position | Rhizopus stolonifer | 2 ferrocytochrome P450 + NADP+ + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADPH-cytochrome P450 reductase | - |
Rhizopus stolonifer |
NADPH-ferrihemoprotein reductase | - |
Rhizopus stolonifer |
NADPH:ferrihemoprotein oxidoreductase | - |
Rhizopus stolonifer |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | together with FMN | Rhizopus stolonifer | |
FMN | together with FAD | Rhizopus stolonifer | |
NADPH | - |
Rhizopus stolonifer |