General Stability | Organism |
---|---|
ability to support benzphetamine N-demethylation activity decreased by about 30% after 1 week of storage at -20°C | Oryctolagus cuniculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Oryctolagus cuniculus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Oryctolagus cuniculus | mixed function oxidase system composed of cytochrome P-450, NADPH-cytochrome c reductase and phospholipids, biotransformation of airborne compounds | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Oryctolagus cuniculus |
Renatured (Comment) | Organism |
---|---|
reconstitution of O-deethylation and N-demethylation activity | Oryctolagus cuniculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | - |
Oryctolagus cuniculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Oryctolagus cuniculus |
Storage Stability | Organism |
---|---|
-20°C, N2-atmosphere, several weeks | Oryctolagus cuniculus |
-20°C, under nitrogen, several weeks | Oryctolagus cuniculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome c + NADPH | - |
Oryctolagus cuniculus | 2 ferrocytochrome c + NADP+ + H+ | - |
? | |
additional information | N-demethylation of benzphetamine | Oryctolagus cuniculus | ? | - |
? | |
additional information | O-deethylation of 7-ethoxycoumarin | Oryctolagus cuniculus | ? | - |
? | |
additional information | mixed function oxidase system composed of cytochrome P-450, NADPH-cytochrome c reductase and phospholipids, biotransformation of airborne compounds | Oryctolagus cuniculus | ? | - |
? |