Application | Comment | Organism |
---|---|---|
medicine | reduction of arylhydroxylamine carcinogens by enzyme and ferricytochrome b5 as a source of individual variability with respect to cancer susceptibility following exposure to arylhydroxylamines | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.22 | - |
N-Hydroxy-4-aminobiphenyl | pH 7.4 | Homo sapiens | |
0.25 | - |
N-hydroxy-2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine | pH 7.4 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ferricytochrome b5 + N-hydroxy-2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine | arylhydroxylamine carcinogen found in grilled meat | Homo sapiens | ferrocytochrome b5 + ? | - |
? | |
ferricytochrome b5 + N-hydroxy-4-aminobiphenyl | arylhydroxylamine carcinogen found in cigarette smoke | Homo sapiens | ferrocytochrome b5 + ? | - |
? |