Cloned (Comment) | Organism |
---|---|
- |
Cereibacter sphaeroides |
Protein Variants | Comment | Organism |
---|---|---|
additional information | enzyme deficient mutants created by insertions at condon 474, 128, and 285 of ptnA | Cereibacter sphaeroides |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Cereibacter sphaeroides | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | Cereibacter sphaeroides | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, major source of NADPH, provides reducing agent for glutathione and is therefore important for the oxidative stress defense | NAD+ + NADPH | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cereibacter sphaeroides | - |
native and enzyme deficient mutant, mutant strain accumulates higher levels of glutathione disulfide | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
no activity detected with the insertion mutants | Cereibacter sphaeroides |
50.8 | - |
native enzyme with acetylpyridine-NAD+ a n NADPH as substrates, pH 7.0 | Cereibacter sphaeroides |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADH + NADP+ | - |
Cereibacter sphaeroides | NAD+ + NADPH | - |
r | |
NADH + NADP+ | links hydride transfer between NAD(H) and NADP(H) to the translocation of protons across membrane, major source of NADPH, provides reducing agent for glutathione and is therefore important for the oxidative stress defense | Cereibacter sphaeroides | NAD+ + NADPH | - |
r | |
NADPH + oxidized 3-acetylpyridine adenine dinucleotide | - |
Cereibacter sphaeroides | NADP+ + reduced 3-acetylpyridine adenine dinucleotide | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD(P)+ | - |
Cereibacter sphaeroides | |
NAD(P)H | - |
Cereibacter sphaeroides |