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Literature summary for 1.5.8.3 extracted from

  • Green, T.; Chen, X.; Ryan, S.; Asch, A.S.; Ruiz-Echevarria, M.J.
    TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells (2013), Prostate, 73, 1561-1575 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.8.3

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sarcosine + H2O + electron-transfer flavoprotein Homo sapiens
-
 glycine + formaldehyde + reduced electron-transfer flavoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
22Rv1 cell
-
 Homo sapiens
-
LNCaP cell
-
 Homo sapiens
-
prostate cancer cell
-
 Homo sapiens
-
RWPE-1 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
sarcosine + H2O + electron-transfer flavoprotein
-
 Homo sapiens glycine + formaldehyde + reduced electron-transfer flavoprotein
-
 ?

Synonyms

Synonyms Comment Organism
SARDH
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction reducing the expression of the enzyme promotes localization of TMEFF2 to the cytoskeleton and also results in increased cellular invasion in tumorigenesis Homo sapiens