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Literature summary for 1.5.5.1 extracted from

  • Araujo, W.L.; Ishizaki, K.; Nunes-Nesi, A.; Larson, T.R.; Tohge, T.; Krahnert, I.; Witt, S.; Obata, T.; Schauer, N.; Graham, I.A.; Leaver, C.J.; Fernie, A.R.
    Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria (2010), Plant Cell, 22, 1549-1563.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.5.1

Protein Variants

Protein Variants Comment Organism
additional information identification of mutants of the ETF/ETFQO complex Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Arabidopsis thaliana 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
reduced electron-transferring flavoprotein + ubiquinone Arabidopsis thaliana
-
 electron-transferring flavoprotein + ubiquinol
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
reduced electron-transferring flavoprotein + ubiquinone
-
 Arabidopsis thaliana electron-transferring flavoprotein + ubiquinol
-
 ?

Synonyms

Synonyms Comment Organism
electron-transfer flavoprotein:ubiquinone oxidoreductase
-
 Arabidopsis thaliana
ETFQO
-
 Arabidopsis thaliana

General Information

General Information Comment Organism
malfunction evaluations of the mutant phenotypes following carbon starvation induced by extended darkness identify similarities to those exhibited by mutants of the ETF/ETFQO complex, metabolic profiling, overview Arabidopsis thaliana
metabolism both isovaleryl-CoA dehydrogenase and 2-hydroxyglutarate dehydrogenase act as electron donors to the ubiquinol pool via an ETF/ETFQO-mediated route, overview. The ETF/ETFQO system can be regarded as a branch of the electron transport system with multiple input sites from seven acyl-CoA dehydrogenases and two N-methyl dehydrogenases, namely, isovaleryl-CoA dehydrogenase and 2-methyl branched-chain acyl-CoA dehydrogenase, as well as glutaryl-CoA dehydrogenase and sarcosine and dimethylglycine dehydrogenases Arabidopsis thaliana
physiological function the functional electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase (ETF/ETFQO) complex supports respiration during carbon starvation. The enzyme is involved in the process of dark-induced senescence Arabidopsis thaliana