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BRENDA support

Literature summary for 1.5.3.6 extracted from

  • Brandsch, R.; Bichler, V.
    Covalent cofactor binding to flavoenzymes requires specific effectors (1989), Eur. J. Biochem., 182, 125-128.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
glycerate-3-phosphate activation of autocatalytical flavinylation Paenarthrobacter nicotinovorans
glycerol-3-phosphate activation of autocatalytical flavinylation Paenarthrobacter nicotinovorans

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli JM101 Paenarthrobacter nicotinovorans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-6-hydroxynicotine + H2O + O2 Paenarthrobacter nicotinovorans
-
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2
-
?

Organism

Organism UniProt Comment Textmining
Paenarthrobacter nicotinovorans
-
formerly Arthrobacter oxidans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-6-hydroxynicotine + H2O + O2
-
Paenarthrobacter nicotinovorans 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2
-
?

Cofactor

Cofactor Comment Organism Structure
FAD
-
Paenarthrobacter nicotinovorans