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Literature summary for 1.5.3.5 extracted from

  • Grether-Beck, S.; Igloi, G.L.; Pust, S.; Schilz, E.; Decker, K.; Brandsch, R.
    Structural analysis and molybdenum-dependent expression of the pAO1-encoded nicotine dehydrogenase genes of Arthrobacter nicotinovorans (1994), Mol. Microbiol., 13, 929-936.
    View publication on PubMed
Search for more literature for 1.5.3.5

Activating Compound

Activating Compound Comment Organism Structure
MoO42- induces enzyme expression activity Paenarthrobacter nicotinovorans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(S)-6-hydroxynicotine + H2O + O2 Paenarthrobacter nicotinovorans
-
 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 transitional product is 6-hydroxy-N-methylmyosmine that hydrolyses spontaneously ?
additional information Paenarthrobacter nicotinovorans enzyme production is induced by growing cells in D,L-nicotine as only source of carbon and nitrogen ?
-
 ?

Organism

Organism UniProt Comment Textmining
Paenarthrobacter nicotinovorans
-
 formerly Arthrobacter oxidans
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-6-hydroxynicotine + H2O + O2
-
 Paenarthrobacter nicotinovorans 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 transitional product is 6-hydroxy-N-methylmyosmine that hydrolyses spontaneously ?
additional information enzyme production is induced by growing cells in D,L-nicotine as only source of carbon and nitrogen Paenarthrobacter nicotinovorans ?
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Paenarthrobacter nicotinovorans

Cofactor

Cofactor Comment Organism Structure
FAD 1 FAD per subunit, non-covalently bound Paenarthrobacter nicotinovorans