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Literature summary for 1.5.1.9 extracted from

  • Hutzler, J.; Dancis, J.
    Lysine-ketoglutarate reductase in human tissues (1975), Biochim. Biophys. Acta, 377, 42-51.
    View publication on PubMed
Search for more literature for 1.5.1.9

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O Homo sapiens involved in lysine catabolism L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Homo sapiens
-
liver
-
 Homo sapiens
-
additional information no activity in: human heart, muscle, skin, brain, spleen, pancreas, adrenal, lung, gut, leukocytes and erythrocytes Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O
-
 Homo sapiens L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+
-
 r
N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O involved in lysine catabolism Homo sapiens L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+
-
 r

pH Stability

pH Stability pH Stability Maximum Comment Organism
4.4
-
 10 min, 60% activity Homo sapiens
4.6 4.9 10 min Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens