Protein Variants | Comment | Organism |
---|---|---|
G121V | kinetic isotope effect study, environmentally coupled tunnelling similar to wild-type | Escherichia coli |
M42W | kinetic isotope effect study, environmentally coupled tunnelling similar to wild-type | Escherichia coli |
M42W/G121V | kinetic isotope effect study, major change in the nature of H transfer, leading to poor reorganization and substantial gating | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+ | kinetic isotope effect analysis, enzyme requires no no donor-acceptor distance fluctuations and thus no gating | Escherichia coli |