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Literature summary for 1.5.1.23 extracted from
- Purification and properties of tauropine dehydrogenase from the shell adductor muscle of the ormer, Haliotis lamellosa (1986), Eur. J. Biochem., 160, 311-318.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| L-lactate | competitive with respect to pyruvate | Haliotis tuberculata lamellosa |  |
| NAD+ | competitive to NADH | Haliotis tuberculata lamellosa | |
| succinate | noncompetitive with respect to taurine and pyruvate | Haliotis tuberculata lamellosa | |
| tauropine | mixed type inhibition with respect to pyruvate and taurine | Haliotis tuberculata lamellosa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | effect of cosubstrate concentration on the Km-value of tauropine and pyruvate | Haliotis tuberculata lamellosa | |
| 0.022 | - |
NADH | - |
Haliotis tuberculata lamellosa | |
| 0.29 | - |
NAD+ | - |
Haliotis tuberculata lamellosa | |
| 3.6 | - |
2-oxovalerate | - |
Haliotis tuberculata lamellosa | |
| 9.04 | - |
tauropine | - |
Haliotis tuberculata lamellosa | |
| 21.1 | - |
2-oxobutanoate | - |
Haliotis tuberculata lamellosa | |
| 235 | - |
Ala | - |
Haliotis tuberculata lamellosa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 38000 | - |
gel filtration | Haliotis tuberculata lamellosa |
| 42000 | - |
1 * 42000, SDS-PAGE | Haliotis tuberculata lamellosa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Haliotis tuberculata lamellosa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Haliotis tuberculata lamellosa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adductor | - |
Haliotis tuberculata lamellosa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 463 | - |
- |
Haliotis tuberculata lamellosa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Ala + pyruvate + NADH | at 6% of the activity with taurine | Haliotis tuberculata lamellosa | ? | - |
? | |
| Taurine + 2-oxobutanoate + NADH | - |
Haliotis tuberculata lamellosa | ? | - |
? | |
| Taurine + 2-oxopentanoate + NADH | - |
Haliotis tuberculata lamellosa | ? | - |
? | |
| Taurine + pyruvate + NADH | r | Haliotis tuberculata lamellosa | Tauropine + NAD+ + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 42000, SDS-PAGE | Haliotis tuberculata lamellosa |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Haliotis tuberculata lamellosa | |
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Release 2023.1 (January 2023)
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