Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D-lactate | weak | Mercenaria mercenaria | |
L-lactate | weak | Mercenaria mercenaria | |
meso-Alanopine | weak | Mercenaria mercenaria | |
succinate | weak | Mercenaria mercenaria |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.32 | - |
pyruvate | - |
Mercenaria mercenaria | |
0.61 | - |
pyruvate | - |
Mercenaria mercenaria | |
2.46 | - |
2-oxobutanoate | - |
Mercenaria mercenaria | |
4.18 | - |
glyoxylate | - |
Mercenaria mercenaria | |
44 | - |
L-2-aminobutanoate | - |
Mercenaria mercenaria | |
173 | - |
L-Ala | - |
Mercenaria mercenaria | |
242 | - |
L-Ala | - |
Mercenaria mercenaria | |
693 | - |
L-Ser | - |
Mercenaria mercenaria |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mercenaria mercenaria | the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mercenaria mercenaria | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Mercenaria mercenaria |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
foot muscle | - |
Mercenaria mercenaria | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Gly + 2-oxobutanoate + NADH | 30% of the activity with pyruvate | Mercenaria mercenaria | ? | - |
? | |
Gly + glyoxylate + NADH | 20% of the activity with pyruvate | Mercenaria mercenaria | ? | - |
? | |
Gly + pyruvate + NADH | - |
Mercenaria mercenaria | D-Strombine + NAD+ + H2O | - |
? | |
L-2-Aminobutanoate + pyruvate + NADH | at 48% of the activity with Gly | Mercenaria mercenaria | ? | - |
? | |
L-Ala + pyruvate + NADH | at 76% of the activity with Gly | Mercenaria mercenaria | meso-Alanopine + NAD+ + H2O | - |
? | |
L-Ser + pyruvate + NADH | at 82% of the activity with Gly | Mercenaria mercenaria | ? | - |
? | |
additional information | the enzyme functions as the terminal dehydrogenase of glycolysis and has a role in maintaining energy production under the stresses of environmental or functional anoxia | Mercenaria mercenaria | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Mercenaria mercenaria | |
NADH | - |
Mercenaria mercenaria |