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Literature summary for 1.5.1.20 extracted from

  • Kim, O.J.; Hong, S.P.; Ahn, J.Y.; Hong, S.H.; Hwang, T.S.; Kim, S.O.; Yoo, W.; Oh, D.; Kim, N.K.
    Influence of combined methionine synthase (MTR 2756A > G) and methylenetetrahydrofolate reductase (MTHFR 677C > T) polymorphisms to plasma homocysteine levels in Korean patients with ischemic stroke (2007), Yonsei Med. J., 48, 201-209.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
additional information MTHFR gene polymorphism C667T interacts with elevated total homocysteine levels leading to an increased risk of ischemic stroke Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + reduced acceptor
-
Homo sapiens 5-methyltetrahydrofolate + oxidized acceptor
-
?

Synonyms

Synonyms Comment Organism
5,10-methylenetetrahydrofolate reductase
-
Homo sapiens
MTHFR
-
Homo sapiens