Literature summary for 1.5.1.20 extracted from

Alcasabas, P.; Ravindranath, Y.; Goyette, G.; Haller, A.; Del Rosario, L.; Lesaca-Medina, M.Y.; Darga, L.; Ostrea, E.M.; Taub, J.W.; Everson, R.B.
5,10-Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and the risk of acute lymphoblastic leukemia (ALL) in Filipino children (2008), Pediatr. Blood Cancer, 51, 178-182.

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Protein Variants

Protein Variants	Comment	Organism
additional information	MTHFR gene polymorphism A1298C is associated with an increased risk for acute lymphoblastic leukemia in Filipino children	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bone marrow	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5,10-methylenetetrahydrofolate + reduced acceptor	-	Homo sapiens	5-methyltetrahydrofolate + oxidized acceptor	-	?

Synonyms

Synonyms	Comment	Organism
5,10-methylenetetrahydrofolate reductase	-	Homo sapiens
MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)