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Literature summary for 1.5.1.20 extracted from

  • Muntjewerff, J.W.; Gellekink, H.; den Heijer, M.; Hoogendoorn, M.L.; Kahn, R.S.; Sinke, R.J.; Blom, H.J.
    Polymorphisms in catechol-O-methyltransferase and methylenetetrahydrofolate reductase in relation to the risk of schizophrenia (2008), Eur. Neuropsychopharmacol., 18, 99-106.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information the C677T gene polymorphism in combination with catechol-O-methyltransferase G324A (Val108/158Met) polymorphism might increase schizophrenia susceptibility Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lymphocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + reduced acceptor
-
Homo sapiens 5-methyltetrahydrofolate + oxidized acceptor
-
?

Synonyms

Synonyms Comment Organism
methylenetetrahydrofolate reductase
-
Homo sapiens
MTHFR
-
Homo sapiens