Cloned (Comment) | Organism |
---|---|
enzyme is encoded by the 2 genes met9 and met11, which can complement the double-mutant strain, but they cannot complement for each other in the met9-deficient and met11-mutant, respectively, DNA and amino acid sequence determination and analysis | Schizosaccharomyces pombe |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
69000 | - |
x * 69000, met9, SDS-PAGE, x *72100, met11, SDS-PAGE | Schizosaccharomyces pombe |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-methyltetrahydrofolate + NADP+ | Schizosaccharomyces pombe | - |
5,10-methylenetetrahydrofolate + NADPH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schizosaccharomyces pombe | - |
genes met9 and met11 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5-methyltetrahydrofolate + NADP+ | - |
Schizosaccharomyces pombe | 5,10-methylenetetrahydrofolate + NADPH | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 69000, met9, SDS-PAGE, x *72100, met11, SDS-PAGE | Schizosaccharomyces pombe |
Synonyms | Comment | Organism |
---|---|---|
methylenetetrahydrofolate reductase | - |
Schizosaccharomyces pombe |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Schizosaccharomyces pombe |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.7 | - |
assay at | Schizosaccharomyces pombe |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Schizosaccharomyces pombe |